The ones I've seen that hold their own weight/make a profit have had teen or adult daughters who baked (and either they owned a bakery or the husband sold their goods once a week or every two weeks at another job where he was already interacting with customers or other workers), home or office cleaning, tutoring, and cosmetology/cutting hair.
The ones I've seen where it's been a time and money pit have been women who are making Jєωelry, make items for craft fairs, have some type of craft shop, cake decorating, and many MLM. I did know a woman who had the pink Cadillac Mary Kay car in the early 90s though. She was a single mother and her child went to private school.
I know one IRL who sells used children's books and children's clothing. She has several FB pages, does the flea market, and it doesn't consume much of her time. Friday and Sat nights nights she may go meet 1 or 2 people and Sunday mornings she does the flea market. She has a VERY large social circle and a husband who pays for her new reliable vehicle and gas. Even when accounting for gas and time she still makes a good profit IMO.
I've heard of model knitters but never met one IRL. I know women who quilt models for a quilt shop but they do it in exchange for buying supplies at wholesale prices. They also have access to a long-arm machine that was purchased by an organization. For someone with a large social circle, they could probably make money doing memory quilts, they seem to sell for a descent rate on Etsy. I can't imagine a young mom of little ones quilting though, she would need childcare.
I for sure did not inherit the "make money gene" so take this with a grain of salt. Just trying to say be cautious from what I've seen, many women do not account for their supplies and funds their husband buys for them or their own investment of time.