Since you mentioned "ladders" and I mentioned "OCW," I thought it would be good to give Immaculatam Hostiam (Should I use the dative case since he is the indirect object? :-) ) this reference:
Dan Newberry's Optimal Charge Weight Load Development..
http://www.ocwreloading.com/
In the above link, Newberry states: "I cleaned the rifle, and shot two fouling shots...."
This brings up an interesting point, one of which I'm not sure if there is a correct answer. Also, this is in relation to precision rifle shooting (not necessarily service rifle).
There seems to be two schools of thought. The first is the above, wherein a cleaned barrel needs to be fired a few times to create some fouling in the barrel. Only upon building up this fouling can it be expected to shoot in a consistent, repeatable manner. Obviously, if one is shooting a match, where many shots may be fired in a single day, this method seems to make sense. The bore is only cleaned periodically, and thus there is always some fouling contained therein, even on cold-bore shots.
The second school of thought, and one advocated by certain snipers, including Carlos Hathcock, was that the first cold-bore shot is the one that counts, and as such, it must always be taken from a cleaned barrel. As one "student" of his relayed, Hathcock would meet him once per day at the range (this was on a military base), wherein he would take only a single shot at a target, noting the weather conditions and where the shot landed relative to point-of-aim. After that one shot, the student was instructed to go back to the armory, and thoroughly clean the bore of the rifle. The student would come back the next day, and repeat. This was done for several weeks/months until the student had built an extensive D.O.P.E. for that rifle/cartridge combination.
I suppose there is a third school of thought, which is as described in the below video, which is to clean only with a solvent after every shoot; no brushes.
From a practical standpoint, my shooting falls into either the first or third school. As I don't have quick access to a range, it would take quite some time to build a D.O.P.E. using the second school of thought. That being said, I have not had a chance to compare either of these methods with one another to see which one is actually better.