Of course, if abortions were "constantly" needed for vaccines, then their use would be 100% prohibited. As it is, it appears that the process is using CLONES/COPIES of the cells, which originally came from abortion long ago. To me, a copy is a new thing, even if it's cellular makeup is identical. Since it's a new thing, then philosophically speaking, it's essence is not the same as the original fetal cells.
Yeah, I making same assumptions and for the sake of discussion presume a good effect is 100% valid (while in the reality we obviously know it is a lie - vaccines bring in a lot of bad, in fact way more then good, if at all).
Now if the process of developing/testing/producing/packaging is the same and the only differentiator here is that for a vaccine A we use 50 years (since the kill) old cell line and for exactly same vaccine B we have 1 month old (since the kill) cell line, it would be an absurd to think that taking A makes one less culpable (due to a "very" "remote" cooperation) than B. As both are equivalent, it is of the same value. (or you could not tell them apart by taking into consideration mere function).
I am not a biochemist nor a theologian of course, but do have a very quite advanced physics background - and I hope I can still logically think - and all looks for me that the main difficulty is understanding what that "CLONES/COPIES of the cells" truly means. It is probably worth mentioning that human body replaces all the cells every 7-10 years (source: a stupid google search). So the existence of the same set of cell is not an essence of our being here.
Personally, I side with an opinion, that there is a direct continuation of an original corpse/cavader of a killed baby, as they share the same DNA, regardless how long the process lasts. The analogy would be, we artificially maintain a body of a dead person or part of it (by e.g. freezing it). Probably a better example would be a frozen embryo. Having said that, it does not matter if the abortion was procured 50 years ago or 5 months ago. Simple as that.
Now, that dramatically shortens number of steps and completely removes time from "the direct line of causality from the abortion to the available fetal cells to the development of the vaccine, to the immunization".
I have also an example where a principle of double effect could be safely used. For instance, a scientists kills a person and using this dead body and his wicked genius comes up with a medical procedure to ... let's say a cure for a leprosy. Now the method itself, which developing took some evil measures, in itself does not, in any form or fashion, rely on the evil which took place. In other words, it is possible that another genius discovered it without a convenient murder which made it easier. Then using that method is morally neutral in any case.