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Author Topic: Not All Monoclonal Antibodies Abortive  (Read 391 times)

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Offline SeanJohnson

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Not All Monoclonal Antibodies Abortive
« on: January 17, 2022, 09:35:00 AM »
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    • From Children of God for Life:

    https://cogforlife.org/2022/01/11/are-monoclonal-antibodies-abortion-tainted-drugs/


    Are Monoclonal Antibodies Abortion-Tainted Drugs?
    by Editor | Jan 11, 2022 | Abortion, News | 17 comments


    Some are and some are not.

    A monoclonal antibody is an antibody (a protein) that is produced by a single clone of cells and has identical antibody molecules on the protein.

    REGEN-COV
    The one of greatest interest these days is REGEN-COV from Regeneron. It is a combination to two monoclonal antibodies, casirivimab (REGN10933) and imdevimab (REGN10987).
    It was developed and tested with the HEK-293T aborted fetal cell lines according to Regeneron’s publication in Cell journal. Another preprint paper in collaboration with Regeneron describes the use of Freestyle 293 cells in the production of REGN10933 and REGN10987, as does this paper in Science journal. We have not been able to verify whether this same production process is used in manufacturing.

    Sotrovimab
    Biologics code is VIR-7831. Lenti X-293Tcells are used in production; see lines 339 and 415. These cells are a subclone of HEK 293. A subclone is a cell that has been genetically modified from a previous instance. This is often done to alter (enhance or attenuate) a cell’s expression characteristics. In this case, the ‘parent’ HEK-293 cell is modified by a DNA segment to enhance the expression of viral proteins and increase the ease of transfection (infection).

    Casirivimab
    Uses ACE2-293, HEK-293T, Freestyle 293cell lines; see above information for REGEN-COV.

    Imdevimab
    Uses ACE2-293, HEK-293T, Freestyle 293cell lines; see above information for REGEN-COV.
    Bamlanivimab
    Biologics code is LY-Cov555. This paper describes the use of HD 293F cells in production of the antibody. The Supplemental Materials of this pre-print paper describe the use of the same cells in production and testing.

    Tocilizumab
    Also called RoActemra. Produced in Chinese Hamster Ovary (CHO) cells; see Product Review. The Assessment Report also does not describe the use of any aborted fetal cell lines.
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    Rom 5: 20 - "But where sin increased, grace abounded all the more."

    Offline SeanJohnson

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    Re: Not All Monoclonal Antibodies Abortive
    « Reply #1 on: January 17, 2022, 09:40:12 AM »
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    • In other words, only the last one mentioned would potentially be free of a link to abortion (pending further research).
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    Rom 5: 20 - "But where sin increased, grace abounded all the more."

    Offline josefamenendez

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    Re: Not All Monoclonal Antibodies Abortive
    « Reply #2 on: January 17, 2022, 10:50:33 AM »
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    • Yes there are some monoclonal antibodies that are not using fetal cells .I think they use mice called hybridomas.they use licit human cells and have been for 40 years.

    But what is missing in the article is that the HEK lines are not the only baby cell culprits being used . Most monoclonal antibodies today are mass produced using humanized mice from fresh killed babies . Regeneron is produced this way

    https://s191.podbean.com/pb/05c334d7c0418a1301c0219514909c3c/61e5926f/data3/fs94/1742339/uploads/Barnhardt-Podcast-163-2021-12-28.mp3?pbss=97df7614-2df6-5758-afd5-ac18475b35d2

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