The Determinants of Mortality
In "Determinants of Mortality" (NBER Working Paper 11963), David Cutler, Angus Deaton, and Adriana Lleras-Muney explore many aspects of this important topic, including the decline in mortality rates over time, differences in mortality across countries, and differences in mortality across groups within countries.
For most of human history, life expectancy has been short - perhaps 25 years for our hunter-gatherer ancestors and only 37 years for residents of England in 1700. Dramatic changes began in the 18th century, with life expectancy in England rising to 41 years by 1820, 50 years by the early 20th century, and 77 years today. The decline in mortality rates was particularly sharp among children. This can be explained by the near elimination of deaths from infectious diseases, formerly the most common cause of death, since the young are most susceptible to infection.
Weighing the various explanations for these mortality reductions, the authors see three phases. From the mid-18th century to the mid-19th century, improved nutrition and economic growth played a large role, as did emerging public health measures. From the mid-19th century to the early 20th century, the delivery of clean water, removal of waste, and advice about personal health practices all led to lower mortality rates, though urbanization had the opposite effect, due to high mortality rates in cities. Since the 1930s, mortality reductions have been driven primarily by medicine, first by vaccination and antibiotics and later by the expensive and intensive interventions that characterize modern medicine.
Looking across countries, there are vast differences in life expectancy, as illustrated in Figure 1. There are also sharp differences in who dies and from what. Deaths among children account for 30 percent of deaths in poor countries but less than 1 percent of deaths in rich countries. Most deaths in rich countries are from cancers and cardiovascular disease, while most deaths in poor countries are from infectious diseases.