Solicitation Number:
HHS-CDC-2017-CancerIncidenceStudy


Notice Type:
Sources Sought




Synopsis:
Added: May 10, 2017 4:38 pm
Introduction: Centers for Disease Control and Prevention (CDC), Agency for Toxic Substances and Disease Registry (ATSDR), Atlanta, GA, is seeking capability statements from all eligible and qualified business concerns. This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain market research information regarding the availability and capability of qualified business sources. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that does not possess the applicable NAICS code should not submit a response to this notice. The applicable NAICS code for this acquisition is 541712 - Research and Development within the Physical, Engineering, and Life Sciences (except Biotechnology) with a size standard of 1,000 employees.

Background. In 2008, the Agency for Toxic Substances and Disease Registry (ATSDR) released "An Assessment of the Feasibility of Conducting Future Epidemiological Studies at USMC Base Camp Lejeune" which concluded that a cancer incidence study of Marines, Naval personnel and civilian workers at Camp Lejeune was feasible. A cancer incidence study would result in a more comprehensive evaluation of associations between exposure to the contaminated drinking water at Camp Lejeune and the incidence of specific cancers among Marines/Navy personnel and civilian employees at Camp Lejeune. In 2014, ATSDR published results of mortality studies of former active duty Marines and Naval personnel and civilian employees stationed at Camp Lejeune that included cause of death information obtained from death certificates for those cohort members who died between 1979 and 2008. Elevated risk for cancers of the kidney, rectum, lung, prostate, leukemias, and multiple myeloma were found in both Marines/Navy personnel and civilian employees.
A cancer incidence study would have a greater capability of evaluating cases of highly survivable cancers than a mortality study. The data obtained for the cancer incidence study would be more accurate and comprehensive. Specifically, the study would include cases not identified through death certificates, and additional information can be obtained from the registry data, such as histological information. In addition, because cancer registry data distinguish between primary and metastatic cancers, there are fewer coding errors than those that occur on death certificates
Purpose and Objectives. The purpose of this effort assess whether there is an association between exposure to the contaminated drinking water at Camp Lejeune and the incidence of specific cancers in approximately 463,922 cohort members, the study will require that vital status and cause of death for decedents be obtained for 425,319 of the cohort members who had not died prior to January 1, 2009 before accessing cancer registry data from up to 55 state, territorial, and federal cancer registries.

[...]