The Singulari quadam is condemning rationalism and indifferentism.
1645 You should inculcate this salutary lesson in the souls of those who exaggerate the strength of human reason to such an extent that they venture by its help to scrutinize and explain even mysteries, although nothing is more inept, nothing more foolish. Strive to withdraw them from such perversity of mind by explaining indisputably that nothing more excellent has been given by the providence of God to man than the authority of divine faith; that this is for us, as it were, a torch in the darkness, a guide which we follow to life; that this is absolutely necessary for salvation; for, "without faith . . . it is impossible to please God" [ Heb. 11:6] and "he that believeth not, shall be condemned"[Mark 16:16].
1646 Not without sorrow we have learned that another error, no less destructive, has taken possession of some parts of the Catholic world, and has taken up its abode in the souls of many Catholics who think that one should have good hope of the eternal salvation of all those who have never lived in the true Church of Christ [see n. 1717]. Therefore, they are wont to ask very often what will be the lot and condition after death of those who have not submitted in any way to the Catholic faith, and, by bringing forward most vain reasons, they make a response favorable to their false opinion. Far be it from Us, Venerable Brethren, to presume on the limits of the divine mercy which is infinite; far from Us, to wish to scrutinize the hidden counsel and "judgments of God" which are 'a great deep" [ Ps. 35:7] and cannot be penetrated by human thought. But, as is Our Apostolic duty, we wish your episcopal solicitude and vigilance to be aroused, so that you will strive as much as you can to drive from the mind of men that impious and equally fatal opinion, namely, that the way of eternal salvation can be found in any religion whatsoever. May you demonstrate with that skill and learning in which you excel, to the people entrusted to your care that the dogmas of the Catholic faith are in no wise opposed to divine mercy and justice.
1647 For, it must be held by faith that outside the Apostolic Roman Church, no one can be saved; that this is the only ark of salvation; that he who shall not have entered therein will perish in the flood; but, on the other hand, it is necessary to hold for certain that they who labor in ignorance of the true religion, if this ignorance is invincible, are not stained by any guilt in this matter in the eyes of God. Now, in truth, who would arrogate so much to himself as to mark the limits of such an ignorance, because of the nature and variety of peoples, regions, innate dispositions, and of so many other things? For, in truth, when released from these corporeal chains "we shall see God as He is" [ 1 John 3:2], we shall understand perfectly by how close and beautiful a bond divine mercy and justice are united; but, as long as we are on earth, weighed down by this mortal mass which blunts the soul, let us hold most firmly that, in accordance with Catholic teaching, there is "one God, one faith, one baptism" [ Eph. 4:5 ]; it is unlawful to proceed further in inquiry.