It's un-respondable-to, because there is no answer for the Protestants he's addressing. A Catholic can answer that faith and reason can coexist in a finite way, but not infinitely. When faith and reason part ways, one must choose faith or reason. Pope Pius XII reminded us that, on this exact question, one must choose faith over reason.
To wit:
Science has proved quite forcefully that Adam and Eve, as described in scripture, are impossible.
God has commanded through the Church that I believe in Adam and Eve, substantially as described in scripture.
Ergo:
I believe in Adam and Eve substantially as described in scripture, without regard to reason.