For some people there's a huge drop off when the pomp and fantasy of being with someone romantically 24/7 wears out. Sounds like the OP's spouse has that in spades plus a large backload of resentment as a result. It's impossible to say how much of his wife's current condition is attributable to the husband, but at this point it sounds like he's long past connecting over anything but daily routine. That's really tough! Her resentment might have even hardened into scathing hatred by the sounds of it. Then again, the OP must know this. In fact this entire thread may be an excuse to meditate on how much he ought to resent her in return. "Nothing that makes sense" says to me he already knows, he's just looking for validation.
But I could definitely be wrong on that.
It may be that a genuinely clueless guy is just figuring out the depths of his wife's animosity towards him. He has my sympathy if that is the case. In addition to examining where he himself may have helped cause the rift, it will be extremely useful to examine the wife's outside interests, coworkers, friends and family for signs of potential malignant influences. However she got to this point, brace yourself OP because it may take all your resources and wits as a man to pull her out of it while keeping your faith in the process.